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Redkite is an Australian cancer charity that supports children and young people with cancer (0–24 years) and their families. We provide essential support from the moment of diagnosis until after treatment finishes, including financial assistance, information and counselling, and education and career support.

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Digital perm SPECIAL OFFER A digital perm is a new technique of creating a shiny and bouncy wave to your hair. As a new trend-setting hairstyling treatment, the digital perm uses temperature controlled rods that are all powered by a machine with a digital display(hence the name). The biggest difference between other perms techniques and the digital perm is the shape and texture of the wave created. A normal perm is known for creating very tight curls which were very popular in the 1980s and makes the waves more prominent when the hair is wet. A digital perm creates the wave as if you have used a curling iron and makes the wave more prominent when the hair is dry against a normal perm. Digital perms also thermally recondition the hair which is a similar process to a straightening perm. Your hair will often feel softer, smoother and shinier after digital perm treatment. Styling A digital perm makes the hair wavy when it is dry, so you must blow-dry with a hairdryer and use your fingers to twist the curls as it dries. Styling is very easy and if you set your curls in the morning, your style will maintain all day and give you loose waves look. You can also revive your curls during the day simply by twisting them with your fingers. Non suitable hair *High damaged hair (Bleach processed hair) *Very fine hair Q&ADigital_Perm Q, Will a digital perm damage my hair? It always depends on the condition of your hair before the process. Hair actually gets damaged by chemical and heating process anyway but with a digital perm, the thermal reconditions the hair to leave it smooth and shiny. Q, How long does the process take? It normally takes approximately 3 hours depending on the hair condition, length and density. Your hair will need to be cut before the digital perm is created for nicer, cleaner waves. Q, How long does the wave/curls last? It also depends on the condition of your hair and the style that you want to achieve. If the hair condition is good then it normally last around 3 - 6 months. Q, Does a digital perm work on bleached hair? By using a solution for high damaged hair, it is possible to do the digital perm on bleached hair but the results will not be as nice as unbleached hair. Q, Is it suitable for short hair? Digital perm is normally suitable for medium to long hair. If there is not enough length, the digital perm will not be able to create very big waves. Q, Does a digital perm give extra the volume from the roots? Digital perms give only a little volume to the roots. It can not be used too close to your scalp because of safety reasons with the heated rods.

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Learn about HEMLIBRA® (emicizumab-kxwh), a hemophilia A treatment now approved for people with hemophilia A with factor VIII inhibitors. See BOXED WARNING. What is HEMLIBRA? HEMLIBRA is a prescription medicine used for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adults and children with hemophilia A with factor VIII inhibitors. What is the most important information I should know about HEMLIBRA? HEMLIBRA increases the potential for your blood to clot. Discontinue prophylactic use of bypassing agents the day before starting HEMLIBRA prophylaxis. Carefully follow your healthcare provider’s instructions regarding when to use an on-demand bypassing agent, and the dose and schedule you should use. HEMLIBRA may cause the following serious side effects when used with aPCC (FEIBA®), including: Thrombotic microangiopathy (TMA). This is a condition involving blood clots and injury to small blood vessels that may cause harm to your kidneys, brain, and other organs. Get medical help right away if you have any of the signs and symptoms of TMA during or after treatment with HEMLIBRA. Blood clots (thrombotic events). Blood clots may form in blood vessels in your arm, leg, lung or head. Get medical help right away if you have any of the signs or symptoms of blood clots during or after treatment with HEMLIBRA. If aPCC (FEIBA®) is needed, talk to your healthcare provider in case you feel you need more than 100 U/kg of aPCC (FEIBA®) total. How should I use Hemlibra? See the detailed “Instructions for Use” that comes with your HEMLIBRA for information on how to prepare and inject a dose of HEMLIBRA, and how to properly throw away (dispose of) used needles and syringes. HEMLIBRA may interfere with laboratory tests that measure how well your blood is clotting and may cause a false reading. Talk to your healthcare provider about how this may affect your care. What are the other possible side effects of HEMLIBRA? The most common side effects of HEMLIBRA include: redness, tenderness, warmth, or itching at the site of injection; headache; and joint pain. These are not all of the possible side effects of HEMLIBRA. You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555. Please see the HEMLIBRA full Prescribing Information and Medication Guide for more important safety information including Serious Side Effects.

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Find information for healthcare professionals about Rituxan® (rituximab), the only FDA-approved treatment proven to induce remission in patients with GPA and MPA. INDICATION STATEMENT - Rituxan® (rituximab), in combination with glucocorticoids, is indicated for the treatment of adult patients with Granulomatosis with Polyangiitis (GPA) (Wegener’s Granulomatosis) and Microscopic Polyangiitis (MPA) - Limitations of Use: Rituxan is not recommended for use in patients with severe, active infections BOXED WARNINGS and Additional Important Safety Information BOXED WARNINGS Infusion Reactions: Rituxan administration can result in serious, including fatal, infusion reactions. Deaths within 24 hours of Rituxan infusion have occurred. Approximately 80% of fatal infusion reactions occurred in association with the first infusion. Monitor patients closely. Discontinue Rituxan infusion for severe reactions and provide medical treatment for Grade 3 or 4 infusion reactions. Severe Mucocutaneous Reactions: Severe, including fatal, mucocutaneous reactions can occur in patients receiving Rituxan. Hepatitis B Virus (HBV) Reactivation: HBV reactivation can occur in patients treated with Rituxan, in some cases resulting in fulminant hepatitis, hepatic failure, and death. Screen all patients for HBV infection before treatment initiation, and monitor patients during and after treatment with Rituxan. Discontinue Rituxan and concomitant medications in the event of HBV reactivation. Progressive Multifocal Leukoencephalopathy (PML): PML, including fatal PML, can occur in patients receiving Rituxan. Warnings and Precautions Rituxan administration can also result in additional serious, including fatal, adverse reactions including: - Tumor lysis syndrome (TLS): Administer aggressive intravenous hydration, anti‑hyperuricemic agents, monitor renal function - Infections: Withhold Rituxan and institute appropriate anti-infective therapy - Cardiac arrhythmias and angina: Discontinue infusions in case of serious or life-threatening events - Bowel obstruction and perforation: Consider and evaluate for abdominal pain, vomiting, or related symptoms - Live virus vaccines: Do not administer live virus vaccines prior to or during Rituxan - Cytopenias: Monitor blood counts at regular intervals Granulomatosis With Polyangiitis (GPA) (Wegener’s Granulomatosis) and Microscopic Polyangiitis (MPA) - Use of concomitant immunosuppressants other than corticosteroids has not been studied in GPA or MPA patients exhibiting peripheral B-cell depletion following treatment with Rituxan. Observe patients with GPA and MPA closely for signs of infection if immunosuppressants other than corticosteroids are used concomitantly - The safety and efficacy of retreatment with Rituxan have not been established in patients with GPA and MPA - Common adverse reactions (≥15%) in the clinical study were infections, nausea, diarrhea, headache, muscle spasms, anemia, and peripheral edema. Other important adverse reactions include infusion reactions You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555. For additional safety information, please see the Rituxan full prescribing information, including BOXED WARNINGS.

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unquestionably samui's finest private luxury retreat, praana resi-dence is an extravagant 5-bedroom hilltop residence literally packed with delights and surprises. praana means 'vital force' and as soon as you enter the impressive grounds through the grand entranceway with ample parking space, you feel the energy of the villa. as you walk over ponds filled with koi carp, passing a private tennis court on the left, tall buddha statues peer down from recesses in the stone clad wall. from the lower level an infinity staircase leads up to the main accommodation, drawing you into this extraordinary villa's appealing indoor and outdoor spaces. inside the property a stylish, two storey central pavillion takes cen-tre stage. the upper level houses a vast, glass walled lounge and banqueting space, with carefully placed contemporary artwork adding style and elegance to the frame. striking crystal chandeliers cascade from the cedar wood ceiling, and the whole room looks out on a backdrop of breathtaking seascapes and tropical forest. two exquisitely appointed bedrooms sit below the living area, each one flowing seamlessly into a glass-walled rainshower room and an indulgent open air bathtub area. leading edge technology and contemporary furnishings add to the experience and the rooms slide open onto a wide terrace that looks over the vast, lawned sky garden and the tempting 30-metre infinity pool that literally pours into the views. the three master bedrooms occupy their own pavillions; two at the front of the villa overlooking the pool and garden, the other at the rear of the property. each boasts its own dramatic, unobstructed island views right from the bed, while inside, the rooms offer indulgent additions like free standing bath tubs and specially imported furnishings and accessories that offer a combination of style and absolute comfort. far more than a home, the praana residence is more like a private hotel. a fully equipped, personal life fitness centre offers tropical views and flat screen tvs to keep you on the treadmill a little longer. there's even a full size, covered muay thai boxing ring where you can learn or practice thailand's famous martial art form. after your work out, soothe your aching muscles in the huge out-door jacuzzi or enjoy a pampering body treatment from the estate's very own on-site spa. when you're ready to kick back and chill a while, catch a movie in the 10-seater private cinema, which is con-nected to a sophisticated apple tv system with a library of over 150 movies and furnished with sink-into leather loungers and equipped with a full surround sound system. with a choice of indoor and al fresco dining spaces, plus a sugges-tion menu that would take months to explore in full, the kitchen's culinary offerings are a fitting accompaniment to the delicious sur-roundings. in fact, with so many spaces and so much to enjoy, this villa is definitely a very special place for a party or celebration. with a full team team of dedicated staff on hand to cater to guests' needs, including an experienced villa manager to answer special requests and assist with bookings and travel arrangements, staying at praana residence is an exuberant experience indeed.

Every 3-4 seconds someone dies of sepsis. Sepsis occurs when the body’s response to an infection damages its own organs and tissues. We are a non-profit movement working to stop sepsis and save lives.

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We all have had one at some point of time. A muscle spasm is a common occurrence, when you extend the body under conditions of dehydration and heat, beyond a stage. When undernourished and overworked, running low on energy and fluids, muscles get spasms (short painful contractions). Through this Buzzle article, I provide an overview of the symptoms, causes and treatment strategies to you to heal muscle spasms. Muscle Function Muscles, with their contractile behavior, are primarily accountable for body motions. In ordinary cases, these voluntary muscles start contracting, when the brain sends electrical signals. These motor neurons stimulate the activation of calcium ions, within the cells of a muscle and act as a catalyst. There are two types of proteins within the muscle cells- Myosin and Actin. The release of calcium ions leads to interaction with proteins, which leads to sliding past one another of proteins of these ions. Recapture of ions leads to unlinking again. Muscle Spasm Occasionally, people have an uneasy feeling of tightness in muscles of legs, neck, arms or their back. Sportspersons, athletes or the folks associated with strenuous tasks get cramps in their own muscles. Both these forms are referred to as muscle spasms. Normally it's characterized by an abrupt burst of unpleasant, painful sense. Every muscle in the body is susceptible to muscle spasm, although it's more common in calf muscles or muscles of the back or neck. Muscle will not loosen after sudden stiffening when the body witness's muscle spasm. When it occurs in legs, it's also known as 'Charley Horse'. Normally, these muscle cramps up the crop from the simple fatigue of muscles, after surprising heavy exercise when the muscle is just not habituated to weights that are additional. It can also occur during pregnancy. Yet, there are few instances when disorders or electrolyte imbalances in neuromuscular functions cause spasms. Also, it could be a complication of certain medicines. Spasms can be catalyzed by the sudden moves, especially a sudden, tweaking move. Stretching that is slow and slow will be a successful option in such scenarios. In conditions that are abnormal, unusual contraction action of muscle cells at any period can result in these spasms. There is specific mechanism between the brain and the spinal cord and motor neurons of the central nervous system to regulate contraction activity. Interruption of the system results in a spasm. Being over sensitive, motor neurons may go bizarre in their functioning. Excitement takes place as muscle sheath itself is quite sensitive, without appropriate contraction. Discharged Calcium ions may not get recaptured in time, resulting in protracted contraction of muscles. Possible reasons behind the interruption of brain mechanism include too stress on particular muscles, injured nerve pathways, stroke, trauma, multiple sclerosis, spinal cord injury. Occasionally, nerve damage can result in a long-term shortening of the muscle, into contracture.

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Learn more about single-bolus TNKase® (tenecteplase) acute myocardial infarction treatment and the 5-second TNKase® dosing and administration. Indication For use in mortality reduction associated with acute myocardial infarction (AMI). Treatment should be initiated as soon as possible after the onset of AMI symptoms. Important Safety Information TNKase therapy in patients with acute myocardial infarction is contraindicated in the following certain situations (eg, active internal bleeding, history of cerebrovascular accident, known bleeding diathesis, severe uncontrolled hypertension) because of an increased risk of bleeding [See CONTRAINDICATIONS in full prescribing information]. The most common complication encountered during TNKase therapy is bleeding. Should serious bleeding (not controlled by local pressure) occur, any concomitant heparin or antiplatelet agents should be discontinued immediately. In certain conditions (eg, recent major surgery, cerebrovascular disease, hypertension) the risk of TNKase therapy may be increased and should be weighed against the anticipated benefits. [See WARNINGS in full prescribing information]. Cholesterol embolism has been reported rarely in patients treated with all types of thrombolytic agents; the true incidence is unknown. Coronary thrombolysis may result in arrhythmias associated with reperfusion. It is recommended that anti-arrhythmic therapy for bradycardia and/or ventricular irritability be available when TNKase is administered. Please see full Prescribing Information for additional important safety information.

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