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NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI) was formally established in 2014 as the focal research program for Synthetic Biology at the National University of Singapore. SynCTI operates as a highly interdisciplinary research core that amalgamates researchers from multiple disciplinary fields, and closely interacts with other research programs within NUS, leveraging on existing research capabilities in synthetic biology that have been developed through funding from local and international organizations. At its initiation, SynCTI will focus on three strategic research thrusts that represent foundational aspects of synthetic biology, and present significant opportunities to advance knowledge and core enabling technologies in synthetic biology